1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity connected to bortezomib, a proteasome inhibitor Employed in the treatment of various myeloma. Its synthesis or review is critical for guaranteeing the purity and safety from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor inside the synthesis of abiraterone acetate, a drug Employed in the remedy of prostate cancer by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-ten-one): A key compound in the synthesis of imatinib, a drug that targets certain forms of cancer, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats many cancers which include breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They are intermediates in the synthesis of gemcitabine, an anti-cancer drug. Their research is very important for optimizing the output process and guaranteeing substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is used to treat breast most cancers, and these intermediates are associated with its generation.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist Employed in the therapy of breast most cancers. Many intermediates help in the synthesis of the drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-16-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug productive in treating cancers which include ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the remedy of colorectal most cancers and small cell lung cancer.
three-Amino-one-hydroxyadamantane (CAS 702-82-nine): This compound is involved in the synthesis of adamantane derivatives, 5-dibenzoate(T6) which have numerous programs, like antiviral Attributes.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for style two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of various gluconic acid derivatives, which can be used in meals, pharmaceutical, and industrial apps.
Canagliflozin Intermediate two: A precursor within the synthesis of canagliflozin, a medication utilized Abiraterone to manage type two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).