1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity connected with bortezomib, a proteasome inhibitor Utilized in the procedure of various myeloma. Its synthesis or analyze is critical for guaranteeing the purity and safety on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug used in the treatment of prostate cancer by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-10-1): A important compound during the synthesis of imatinib, a drug that targets precise types of most cancers, like Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers which include breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): They're intermediates while in the synthesis of gemcitabine, an anti-cancer drug. Their review is vital for optimizing the creation method and guaranteeing superior purity.
Lapatinib (7a Intermediate (CAS NO. 231278-84-5): Lapatinib is utilized to treat breast cancer, and these intermediates are involved with its output.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the therapy of breast cancer. Many intermediates assist in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug effective in treating cancers for example ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy CAS NO. 134790-39-9 drug used in the procedure of colorectal cancer and small mobile lung most cancers.
three-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is involved in the synthesis of adamantane derivatives, which have a variety of apps, including antiviral properties.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for sort two diabetic issues that inhibits the enzyme DPP-4 to control blood sugar levels.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of various gluconic acid derivatives, which are Utilized in food stuff, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate 2: A precursor in the synthesis of canagliflozin, a medication utilised to deal with variety two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).